Upstream Bioprocessing

In our new class C cleanroom we can ferment microorganisms up to biosafety level BSL2. The facility is designed to work safely with genetically modified organisms up to containment level ML-IIK for the expression of recombinant proteins . A 50 L fermentor in combination with highly skilled personnel can scale up the biological production of the (non-)clinical studies that are ahead of your research.

Downstream Bioprocessing

Our state-of-the-art downstream equipment provides us with many strategies for the downstream processing of your biomolecules. We possess a stimulated moving bed (SMB) chromatograph device, that allows us to perform more efficient, continuous chromatography compared to conventional batch chromatography devices.

In combination with different volume sizes of Tangential Flow Filtration (TFF) machines, we can concentrate and diafiltrate over a large volume range. The combination of these methods prepares us optimally for the purification of your biomolecules.

Fill & Finish activities

Besides Drug Substance development and manufacturing, we can offer you a smooth transition towards a required Drug Product formulation within our adjacent aseptic Fill & Finish facilities. We have in-house access to several filling lines ranging from simple manual fill for small batches up until a fully automated filling machine that can aseptically fill vials or pre-filled syringes in large quantities.

Lyophilisation - Cytotoxic compounds & (flammable) Organic solvents

A fully lyophilisation unit is available that can be used for cytotoxic compounds and (flammable) organic solvents. Our IMP department is available for the blinding of study medication, randomisation, packaging and labelling of clinical trial medication as well as release for use in a clinical setting.

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Click here for our brochure Biotechnology.